Minoxidil (Oral)

What are the possible side effects of oral Minoxidil?

Possible side effects of oral minoxidil can include:

1. Fluid retention (edema): Swelling in the hands, feet, or legs due to fluid buildup.
2. Low blood pressure: Dizziness, lightheadedness, or fainting may occur, especially upon standing up.
3. Rapid or irregular heartbeat: Palpitations or changes in heart rhythm can happen in some individuals.
4. Shortness of breath: Difficulty breathing or tightness in the chest.
5. Unwanted hair growth: Excessive hair growth in undesirable areas.
6. Weight gain: Rapid or unexplained weight gain might occur.

Note that oral minoxidil is not typically prescribed for hair loss, as the topical solution has a lower risk of systemic side effects. It’s essential to consult a healthcare provider before using minoxidil pills, especially for off-label purposes.

What may interact with oral Minoxidil?

Oral minoxidil can interact with several medications, potentially affecting the drug’s effectiveness or increasing the risk of side effects. Some common drug interactions include:

1. Diuretics: Combining minoxidil with diuretics, like hydrochlorothiazide or furosemide, may lead to an excessive drop in blood pressure or increased risk of electrolyte imbalances.
2. Beta-blockers: Medications such as propranolol or metoprolol may interact with minoxidil, potentially causing a significant decrease in blood pressure.
3. Vasodilators: When used with other vasodilators like hydralazine or nitrates, minoxidil may amplify the blood pressure-lowering effects, increasing the risk of hypotension.
4. Guanethidine: Minoxidil may decrease the effectiveness of guanethidine, an antihypertensive drug.

This list is not exhaustive, and other medications or supplements may interact with oral minoxidil.